760177-72-8Relevant academic research and scientific papers
Enantioselective (3+2) cycloaddition: Via N-heterocyclic carbene-catalyzed addition of homoenolates to cyclic N -sulfonyl trifluoromethylated ketimines: Synthesis of fused N-heterocycle γ-lactams
Zhang, Zhen-Zhen,Zhang, Yongna,Duan, Hui-Xin,Deng, Zhuo-Fei,Wang, You-Qing
supporting information, p. 1553 - 1556 (2020/02/13)
An enantioselective (3+2) cycloaddition of enals and cyclic N-sulfonyl trifluoromethyl ketimines via N-heterocyclic carbene-catalyzed homoenolate addition is described. This reaction can efficiently construct fused N-heterocycle γ-lactams bearing two adjacent chiral centers with >20?:?1 dr and 94-99% ee, with one chiral center as a trifluoromethylated α-tetrasubstituted carbon stereocenter.
Synthesis of functionalized arenes
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Paragraph 0058; 0059; 0060, (2015/04/22)
The present invention relates to methods of preparing (cyclo)alkoxy-((cyclo)alkylsulfanyl)benzenes, (cyclo)alkoxy-((cyclo)alkylsulfinyl)benzenes and (cyclo)alkoxy-((cyclo)alkylsulfonyl)benzenes of general formula (I): as well as to intermediate compounds useful in the preparation of said compounds.
