760181-75-7

Upstream product

• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 760181-80-4 (S)-2,4-Bis-benzyloxy-butyric acid (1R,2R)-1-ethyl-2-hydroxy-pent-4-enyl ester 
• 109199-96-4 (2S)-2,4-dibenzyloxybutanal 
• 760181-72-4 (R)-2-(4-methoxybenzyloxy)pent-4-en-1-ol 
• 760181-73-5 (3R,4R)-4-(4-Methoxy-benzyloxy)-hept-6-en-3-ol 
• 760181-74-6 (S)-2,4-Bis-benzyloxy-butyric acid (1R,2R)-1-ethyl-2-(4-methoxy-benzyloxy)-pent-4-enyl ester 

Downstream Products

• 760181-76-8 Chloro-acetic acid (S)-2,4-bis-benzyloxy-1-((1R,2R)-1-ethyl-2-triisopropylsilanyloxy-pent-4-enyloxy)-butyl ester 

Relevant academic research and scientific papers

A new approach to the synthesis of cyclic ethers via the intermolecular allylation of α-acetoxy ethers and ring-closing metathesis

A concise synthesis of the isolaurepinnacin skeleton 6 was achieved via the intermolecular allylation of the α-acetoxy ether 3 followed by ring-closing metathesis. This methodology was successfully applied to the convergent synthesis of the oxocene 15, an advanced synthetic intermediate for the total synthesis of laurencin.