76019-13-1 Usage
Uses
Used in Pharmaceutical Industry:
5,6-Dimethoxy-1,2,3,4-tetrahydroisoquinoline is used as a serotonin receptor antagonist for its potential role in treating conditions related to serotonin dysregulation. Its ability to modulate serotonin signaling pathways may contribute to the management of disorders associated with this neurotransmitter.
Used in Neurodegenerative Disease Treatment:
In the field of neurodegenerative diseases, 5,6-dimethoxy-1,2,3,4-tetrahydroisoquinoline is utilized for its neuroprotective effects. Its potential to shield neurons from degeneration and protect the nervous system makes it a candidate for the development of treatments aimed at slowing or halting the progression of such diseases.
Used in Anti-Inflammatory Applications:
5,6-Dimethoxy-1,2,3,4-tetrahydroisoquinoline is employed as an anti-inflammatory agent due to its capacity to reduce inflammation. This property could be beneficial in the treatment of various inflammatory conditions, where modulation of the inflammatory response is crucial for disease management and symptom relief.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, 5,6-dimethoxy-1,2,3,4-tetrahydroisoquinoline serves as a subject of interest for its unique structure and pharmacological activities. Researchers are exploring its potential as a lead compound in the development of new drugs targeting a range of therapeutic areas, including central nervous system disorders and inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 76019-13-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,0,1 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 76019-13:
(7*7)+(6*6)+(5*0)+(4*1)+(3*9)+(2*1)+(1*3)=121
121 % 10 = 1
So 76019-13-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H15NO2/c1-13-10-3-4-11(14-2)9-7-12-6-5-8(9)10/h3-4,12H,5-7H2,1-2H3
76019-13-1Relevant academic research and scientific papers
Shinohara, Tatsumi,Takeda, Akira,Toda, Jun,Ueda, Yoko,Kohno, Michiyo,Sano, Takehiro
, p. 918 - 927 (1998)
A synthesis of 1,2,3,4-tetrahydroisoquinolines (TIQs) (23) with one and two methoxyl groups at various positions of the benzene ring was achieved via the intramolecular cyclization of N-(aryl)methyl-2- (phenylsulfinyl)ethylamines (9) using the Pummerer reaction as a key step. The reaction was carried out by using trifluoroacetic anhydride (TFAA) (method A) or TFAA-BF3 · Et2O (method B). The cyclization to 4-SPhTIQs (11) proceeded effectively when the reaction center at the benzene ring was electronically activated by a methoxyl group. In the reaction of the sulfoxide (9e) having two OMe groups at ortho- and para-positions a different cyclization reaction leading to a benzothiazepine (12) was observed, indicating that the high nucleophilicity of the benzene ring caused the unexpected reaction prior to the cyclization to 4-SPhTIQ (11e). The route starting from methoxylated benzaldehydes (5) was proved to provide an efficient and convenient method of TIQ synthesis which should be complementary to the well known Pictet-Spengler method.
