76029-50-0

Basic information

• Product Name: cyclopentyloxy amine
• Synonyms: cyclopentyloxy amine;O-CYCLOPENTYLHYDROXYLAMINE
• CAS NO: 76029-50-0
• Molecular Formula: C₅H₁₁NO
• Molecular Weight: 101.14694
• Mol File: 76029-50-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: cyclopentyloxy amine(CAS DataBase Reference)
• NIST Chemistry Reference: cyclopentyloxy amine(76029-50-0)
• EPA Substance Registry System: cyclopentyloxy amine(76029-50-0)

Safety Data

• Hazardous Substances Data: 76029-50-0(Hazardous Substances Data)

Usage

General Description

Cyclopentyloxy amine is an organic compound with the chemical formula C5H11NO. This chemical is a cyclopentyl derivative of amine, containing a five-membered ring structure. It is commonly used as a building block in the synthesis of various pharmaceutical and agrochemical products. Cyclopentyloxy amine is a versatile intermediate in organic synthesis, and its unique chemical structure makes it a valuable starting material for the production of a wide range of compounds. This chemical has potential applications in the development of new drugs, as well as in the manufacturing of specialty chemicals.

Upstream product

• 96-41-3 Cyclopentanol 
• 137-43-9 Cyclopentyl bromide 
• 54224-24-7 2-(cyclopentyloxy)-1H-isoindole-1,3(2H)-dione 

Downstream Products

• 880472-47-9 C₁₅H₁₈ClF₃N₂O₃S 
• 1033780-24-3 C₂₅H₂₅ClN₄O₆S 
• 1033780-25-4 C₂₅H₂₄Cl₂N₄O₅S 
• 1033780-02-7 (E)-4-{3-[2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-acetylamino]-pyrazol-1-ylmethyl}-benzamide 
• 1033780-15-2 (E)-N-[1-(3-acetylamino-benzyl)-1H-pyrazol-3-yl]-2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-acetamide 
• 1033780-00-5 (E)-4-{3-[2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-acetylamino]-pyrazol-1-ylmethyl}-benzoic acid methyl ester 
• 1033780-08-3 (E)-N-(6-chloro-benzothiazol-2-yl)-2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-acetamide 
• 1033780-14-1 (E)-N-(5-benzyl-[1,3,4]thiadiazol-2-yl)-2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-acetamide 
• 1033780-07-2 (E)-2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-N-(6-methoxy-benzothiazol-2-yl)-acetamide 
• 1033780-12-9 (E)-N-(3-benzyl-[1,2,4]thiadiazol-5-yl)-2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-acetamide 
• 1033780-01-6 (E)-2-[2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-acetylamino]-thiazole-5-carboxylic acid amide 
• 1033780-16-3 (E)-2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-N-(1-pyridin-3-ylmethyl-1H-pyrazol-3-yl)-acetamide 
• 1033779-99-5 (E)-N-benzothiazol-2-yl-2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-acetamide 
• 1033780-13-0 (E)-2-(3-chloro-4-methanesulfonyl-phenyl)-2-cyclopentyloxyimino-N-(1-propyl-1H-pyrazol-3-yl)-acetamide 

Relevant articles and documents

A New Dioxazolone for the Synthesis of 1,2-Aminoalcohols via Iridium(III)-Catalyzed C(sp3)?H Amidation

Vicinal aminoalcohols are widespread structural motifs in bioactive molecules. We report the development of a new dioxazolone reagent containing a p-nitrophenyldifluoromethyl group, which 1. displays a good safety profile; 2. shows a remarkably high react

Oxime glucokinase activators

Disclosed herein are pyrazole glucokinase activators of the formula (I): that are useful for the treatment of metabolic diseases and disorders.

Studies on anti-MRSA parenteral cephalosporins II. Synthesis and antibacterial activity of 7 β-[2-(5-Amino-1,2,4-thiadiazol-3-yl)- 2(Z)-alkoxyiminoacetamido]-3(substituted imidazo[1,2-b] pyridazinium-1-yl)methyl-3-cephem-4-carboxylates and related compounds

In an effort to discover a novel cefozopran (CZOP) derivative having excellent antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA), we performed chemical modification of the alkoxyimino moiety and imidazo[1,2-b]pyridazinium group of CZOP. Among the prepared compounds, the cyclopentyloxyimino derivative 7β-[2-(5- amino-1,2, 4-thiadiazol-3-yl)-2(Z) -cyclopentyloxyiminoacetamido] -3-(3,6-diaminoimidazo[1,2- b]pyridazinium-1-yl)methyl-3-cephem-4-carboxylate (20g) showed the most potent anti-MRSA activity, reflecting its high affinity (IC50=1.6μg/ml) for penicillin binding protein 2' (PBP2'), although its anti-MRSA activity was slightly inferior to that of vancomycin (VCM). In experimental systemic infection in mice, however, 20g showed activity comparable to that of VCM against MRSA. In addition, 20g showed activity similar or slightly inferior to that of CZOP against Pseudomonas aeruginosa both in vitro and in vivo. Considering its favorable antibacterial activity profile, 20g was considered to be the most promising CZOP derivative for further studies.