76044-33-2

Upstream product

• 3310-41-6 4-hydrazinylpyrimidin-2(1H)-one 
• 1663-61-2 triethoxymethylbenzene 

Downstream Products

• 76044-38-7 5-chloro-2-phenyl-s-triazolo<1,5-c>pyrimidine 
• 76044-58-1 N-acetoxy-N'-(2-phenyl-s-triazolo<1,5-c>pyrimidin-5-yl)formamidine 
• 76044-52-5 N-hydroxy-N'-(2-phenyl-s-triazolo<1,5-c>pyrimidin-5-yl)formamidine 
• 76044-47-8 N,N-dimethyl-N'-(2-phenyl-s-triazolo<1,5-c>pyrimidin-5-yl)formamidine 
• 76044-64-9 8-phenylbis-s-triazolo<1,5-a:1',5'-c>pyrimidine 

Relevant academic research and scientific papers

The first reliable, general synthesis of the 5-oxo derivatives of 5,6-dihydro-1,2,4-triazolo[4,3-c]-pyrimidine and the rates of isomerization of the [4,3-c] compounds into their [1,5-c] isomers

This paper describes a reliable synthesis of the 5-oxo derivatives (8) of 5,6-dihydro-1,2,4-triazolo[4,3-c]pyrimidine, by the reaction of 2-oxo-1,2-dihydropyrimidin-4-ylhydrazines (7) with the appropriate triethyl orthoesters in trifluoroacetic acid below 30°C or by the oxidative cyclization of their aldehyde hydrazones (10) with 70% nitric acid in trifluoroacetic acid below 40°C, and the rates of isomerization of the [4,3-c] compounds (8) into the [1,5-c] isomers (9).

Bis-s-triazolopyrimidine and Some Simple Derivatives

A general synthetic route to the new tricyclic system bis-s-triazolopyrimidine, is reported.Thus the parent heterocycle (11a) is prepared from the key bicyclic intermediate, s-triazolopyrimidin-5-ylamine (7a), through the correspondi