76055-95-3

Upstream product

• 76055-90-8 2-(2-hydroxymethyl-4,5-dimethoxyphenyl)-3-(3,4-dimethoxyphenyl)-N-methylpropionamide 
• 76055-91-9 4-(3,4-dimethoxybenzyl)-6,7-dimethoxyisochroman-3-one 
• 76055-93-1 3-(3,4-dimethoxyphenyl)-2-(2-hydroxymethyl-4,5-dimethoxyphenyl)-NN-dimethylpropionamide 
• 76055-94-2 3-(3,4-dimethoxyphenyl)-2-(2-formyl-4,5-dimethoxyphenyl)-NN-dimethylpropionamide 

Relevant academic research and scientific papers

Electrochemical Oxidation of Aromatic Ethers. Part 6. Oxidation of 4-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline and Attempted Synthesis of 4-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,4-dihydro-3(2H)-isoquinoline

The cyclisation of 3-(2,4-dimethoxybenzyl)-2-(2-hydroxymethyl-4,5-dimethoxyphenyl)-N-methylpropionamide (5) and related compounds does not yield 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methyl-1,4-dihydro-3(2H)-isoquinolone, but gives instead dibenzocycloheptane derivatives.Anodic oxidation of 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline affords the corresponding 3,4-dihydroisoquinolinium and 4-(3,4-dimethoxybenzylidene)-6,7-dimethoxy-2-methyl-1,4-dihydroisoquinolinium salts.No intramolecularly aryl-aryl coupled products are isolated and the implication of this result on the design of substrates for the synthesis of biphenyl derivatives is discussed.