76056-04-7

Upstream product

• 16135-41-4 6,7-dimethoxy-3,4-dihydro-1H-2-benzopyran-3-one 
• 73053-80-2 ethyl 2-(bromomethyl)-4,5-dimethoxyphenylacetate 
• 16135-42-5 1,4-dihydro-6,7-dimethoxy-2-methylisoquinolin-3(2H)-one 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 

Downstream Products

• 76056-05-8 4-(3,4-dimethoxybenzoyl)-6,7-dimethoxy-2-methyl-1,4-dihydro-3(2H)-isoquinolone 

Relevant academic research and scientific papers

Electrochemical Oxidation of Aromatic Ethers. Part 6. Oxidation of 4-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline and Attempted Synthesis of 4-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,4-dihydro-3(2H)-isoquinoline

The cyclisation of 3-(2,4-dimethoxybenzyl)-2-(2-hydroxymethyl-4,5-dimethoxyphenyl)-N-methylpropionamide (5) and related compounds does not yield 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methyl-1,4-dihydro-3(2H)-isoquinolone, but gives instead dibenzocycloheptane derivatives.Anodic oxidation of 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline affords the corresponding 3,4-dihydroisoquinolinium and 4-(3,4-dimethoxybenzylidene)-6,7-dimethoxy-2-methyl-1,4-dihydroisoquinolinium salts.No intramolecularly aryl-aryl coupled products are isolated and the implication of this result on the design of substrates for the synthesis of biphenyl derivatives is discussed.