Transforming Growth Factors (TGFs) are a group of polypeptide proteins that play a crucial role in regulating cell growth, differentiation, and other cellular functions. They can stimulate or inhibit cell growth, depending on the context, and are essential for normal development and tissue homeostasis. TGFs are involved in wound healing, immune response, and the regulation of the extracellular matrix. They exert their effects by binding to specific receptors on the cell surface and activating intracellular signaling pathways that lead to changes in gene expression and cellular behavior. Dysregulation of TGF signaling has been implicated in various diseases, including cancer, fibrosis, and autoimmune disorders. Overall, TGFs are critical for maintaining tissue integrity and function.
76057-06-2
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Basic information
- Product Name: Transforming Growth Factors
- Synonyms: Transforming Growth Factors
- CAS NO:76057-06-2
- Molecular Formula: C23H24N4O
- Molecular Weight: 372.46286
- EINECS: N/A
- Product Categories: N/A
- Mol File: 76057-06-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Transforming Growth Factors(CAS DataBase Reference)
- NIST Chemistry Reference: Transforming Growth Factors(76057-06-2)
- EPA Substance Registry System: Transforming Growth Factors(76057-06-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 76057-06-2(Hazardous Substances Data)
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76057-06-2 Usage
Uses
Used in Regenerative Medicine:Transforming Growth Factors are used as growth factors for promoting tissue repair and regeneration. They stimulate the proliferation and differentiation of various cell types, contributing to the healing process and restoration of damaged tissues.
Used in Cancer Research and Therapy:
Transforming Growth Factors are used as targets for cancer research and therapy. They play a dual role in cancer, acting as tumor suppressors in the early stages and promoting tumor growth and metastasis in advanced stages. Understanding the mechanisms of TGF signaling in cancer can help develop targeted therapies to modulate their activity and improve treatment outcomes.
Used in Fibrotic Disease Treatment:
Transforming Growth Factors are used as therapeutic targets for treating fibrotic diseases. TGFs are known to promote the accumulation of extracellular matrix components, leading to tissue fibrosis. Inhibiting TGF signaling can help reduce fibrosis and improve organ function in diseases such as pulmonary fibrosis, liver cirrhosis, and kidney fibrosis.
Used in Autoimmune Disease Research:
Transforming Growth Factors are used as research tools for understanding the pathogenesis of autoimmune diseases. Dysregulation of TGF signaling has been implicated in various autoimmune disorders, such as systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis. Studying the role of TGFs in these diseases can provide insights into potential therapeutic targets and treatment strategies.
Used in Wound Healing and Tissue Repair:
Transforming Growth Factors are used as wound healing agents for promoting tissue repair and regeneration. They stimulate the migration, proliferation, and differentiation of various cell types involved in the wound healing process, including fibroblasts, endothelial cells, and immune cells. TGFs also regulate the synthesis and deposition of extracellular matrix components, contributing to the formation of granulation tissue and the restoration of tissue integrity.
Check Digit Verification of cas no
The CAS Registry Mumber 76057-06-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,0,5 and 7 respectively; the second part has 2 digits, 0 and 6 respectively.Calculate Digit Verification of CAS Registry Number 76057-06:
(7*7)+(6*6)+(5*0)+(4*5)+(3*7)+(2*0)+(1*6)=132
132 % 10 = 2
So 76057-06-2 is a valid CAS Registry Number.
76057-06-2Upstream product
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Transforming Growth Factors
