76060-08-7

Upstream product

• 6628-86-0 5-chloro-2-nitrobenzaldehyde 
• 4760-34-3 N-methyl-1,2-phenylenediamine 
• 88-73-3 2-Chloronitrobenzene 
• 612-28-2 2-nitro-N-methylaniline 
• 76060-05-4 2-(5-chloro-2-nitrophenyl)-1-methyl-2,3-dihydrobenzimidazole 

Downstream Products

• 60418-30-6 2-(2-azido-5-dimethylaminophenyl)-1-methylbenzimidazole 
• 60418-29-3 2-(2-amino-5-dimethylaminophenyl)-1-methylbenzimidazole 
• 76060-09-8 2-(5-dimethylamino-2-nitrophenyl)-1-methylbenzimidazole 

Relevant academic research and scientific papers

2-Arylbenzothiazole, benzoxazole and benzimidazole derivatives as fluorogenic substrates for the detection of nitroreductase and aminopeptidase activity in clinically important bacteria

A series of 2-(2-nitrophenyl)benzothiazole 7, 2-(2-nitrophenyl)benzoxazole 10 and 2-(2-nitrophenyl)benzimidazole 13 derivatives have been synthesised and assessed as indicators of nitroreductase activity across a range of clinically important Gram negativ

Competitive Cyclisations of Singlet and Triplet Nitrenes. Part 9. 2-(2-Nitrophenyl)-benzothiazoles and -benzimidazoles

2-(2-Nitrophenyl)benzothiazole, produced by deoxygenation of the corresponding nitro-compound or by thermolysis or photolysis of the related azide, gives indazolobenzothiazole by attack on the benzothiazole nitrogen.Similar attack of the nitrene in 2-(2-nitrophenyl)benzimidazoles gives benzimidazoindazoles in good yield.However, with an appropriate 1-substituent in the benzimidazole (e.g.Me or CHMe2) the nitrene in its triplet state (generated by acetophenone-sensitised photolysis or by thermolysis of the azide bearing a 4-dimethylamino-group) preferentially attacks this substituent giving benzimidazoquinazolines.