76063-14-4Relevant academic research and scientific papers
Efficient Domino Hydroformylation/Benzoin Condensation: Highly Selective Synthesis of α-Hydroxy Ketones
Dong, Kaiwu,Sang, Rui,Soule, Jean-Francois,Bruneau, Christian,Franke, Robert,Jackstell, Ralf,Beller, Matthias
supporting information, p. 18033 - 18037 (2015/12/24)
An improved domino hydroformylation/benzoin condensation to give α-hydroxy ketones has been developed. Easily available olefins are smoothly converted into the corresponding α-hydroxy ketones in high yields with excellent regioselectivities. Key to success is the use of a specific catalytic system consisting of a rhodium/phosphine complex and the CO2 adduct of an N-heterocyclic carbene. 2 for 1: An improved domino hydroformylation/benzoin condensation of olefins has been developed in the presence of a specific catalytic system consisting of a rhodium/phosphine complex and the CO2 adduct of an N-heterocyclic carbene.
Exerting control over the acyloin reaction
Donohoe, Timothy J.,Jahanshahi, Ali,Tucker, Michael J.,Bhatti, Farrah L.,Roslan, Ishmael A.,Kabeshov, Mikhail,Wrigley, Gail
supporting information; experimental part, p. 5849 - 5851 (2011/06/27)
A synthetic method for conducting the acyloin reaction using electron transfer in solution is reported. By linking two esters via their oxygen atoms, it was possible to perform crossed acyloin reactions between two different ester functionalities and display a high degree of preference for an intramolecular coupling process.
Addition-type oxidation of silylalkene using ozone: An efficient approach for acyloin and its derivatives
Igawa, Kazunobu,Kawasaki, Yuuya,Tomooka, Katsuhiko
, p. 233 - 235 (2011/05/14)
Acyloins are efficiently synthesized in three steps from alkynes via ydrosilylation followed by an addition-type ozone oxidation and hydrogenation. The key intermediate α-silylperoxy ketone is convertible to not only acyloin but also O-silylated acyloin and diketone.
REDUCTIVE COUPLING OF S-(2-PYRIDYL) ALIPHATIC THIOATES BY USE OF BIS(1,5-CYCLOOCTADIENE)NICKEL
Onaka, Makoto,Matsuoka, Yoshio,Mukaiyama, Teruaki
, p. 905 - 906 (2007/10/02)
S-(2-Pyridyl) aliphatic thioates are reductively dimerized to give α-diketones and α-hydroxy ketones on treatment with bis(1,5-cyclooctadiene)nickel at 40 deg C.
