7607-49-0

Upstream product

• 368-00-3 1-chloro-2-(4-fluorobenzyl)benzene 
• 1765-93-1 4-fluoroboronic acid 
• 22115-41-9 2-(bromomethyl)benzonitrile 
• 623-26-7 terephthalonitrile 
• 1609468-92-9 C₂₀H₂₄FNO₄ 

Downstream Products

• 388-21-6 (2-benzoylphenyl)(4-fluorophenyl)methanone 
• 394-76-3 2-(4-fluoro-benzyl)-benzophenone 

Relevant academic research and scientific papers

Anodic benzylic C(sp3)-H amination: Unified access to pyrrolidines and piperidines

An electrochemical aliphatic C-H amination strategy was developed to access the important heterocyclic motifs of pyrrolidines and piperidines within a uniform reaction protocol. The mechanism of this unprecedented C-H amination strategy involves anodic C-H activation to generate a benzylic cation, which is efficiently trapped by a nitrogen nucleophile. The applicability of the process is demonstrated for 40 examples comprising both 5- and 6-membered ring formations.

Visible-Light-Mediated Aromatic Substitution Reactions of Cyanoarenes with 4-Alkyl-1,4-dihydropyridines through Double Carbon-Carbon Bond Cleavage

Novel aromatic substitution reactions of cyanoarenes with 4-alkyl-1,4-dihydropyridines as alkylating reagents in the presence of a catalytic amount of a photoredox catalyst proceed smoothly to give the corresponding alkyl-substituted arenes in good to high yields. The present reaction system realizes a novel C-C bond-forming reaction between two fragments generated from the C-C bond-cleavage reactions of two independent substrates.