76076-40-9Relevant academic research and scientific papers
Construction of All-Carbon Chiral Quaternary Centers through CuI-Catalyzed Enantioselective Reductive Hydroxymethylation of 1,1-Disubstituted Allenes with CO2
Qiu, Jia,Gao, Shen,Li, Chaopeng,Zhang, Lei,Wang, Zheng,Wang, Xiaoming,Ding, Kuiling
, p. 13874 - 13878 (2019/11/11)
A catalytic enantioselective construction of all-carbon chiral quaternary centers through reductive hydroxymethylation of 1,1-disubstituted allenes with CO2 has been developed. In the presence of a copper/Mandyphos catalyst, CO2 is t
Synthesis of α-Quaternary Formimides and Aldehydes through Umpolung Asymmetric Copper Catalysis with Isocyanides
Hojoh, Kentaro,Ohmiya, Hirohisa,Sawamura, Masaya
supporting information, p. 2184 - 2187 (2017/02/23)
A highly regio- and enantioselective copper-catalyzed three-component coupling of isocyanides, hydrosilanes, and γ,γ-disubstituted allylic phosphates/chlorides to afford chiral α-quaternary formimides was enabled by the combined use of our original chiral
ASYMMETRIC INDUCTION IN THE SIGMATROPIC REARRANGEMENT VIA CHIRAL AMMONIUM YLIDES
Hiroi, Kunio,Nakazawa, Kumiko
, p. 1077 - 1080 (2007/10/02)
The asymmetric sigmatropic rearrangements of the chiral ammonium chlorides (E)-(3a,b) were achieved upon treatment with t-BuOK followed by acidic hydrolysis of the aminonitriles (5a,b) obtained to give (R)-(+)-2-methyl-2-phenyl-3-butenal (6).The rea
