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Oxamate-diaminohexyl-sepharose is a specialized chemical compound designed for use in chromatography, specifically for the purification of proteins. It consists of a cross-linked agarose resin with oxamate, a competitive inhibitor of lactate dehydrogenase, covalently attached to a diaminohexyl spacer arm. This unique structure enables the selective binding and purification of lactate dehydrogenase and similar enzymes from complex mixtures, providing a reversible and efficient method for affinity purification.

76082-51-4

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76082-51-4 Usage

Uses

Used in Biochemistry Research:
Oxamate-diaminohexyl-sepharose is used as a chromatographic medium for the specific binding and purification of lactate dehydrogenase and other lactate dehydrogenase-like enzymes. Its application allows researchers to isolate and study these enzymes in a controlled manner, facilitating the investigation of their functions, mechanisms, and potential applications in various biological processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, oxamate-diaminohexyl-sepharose is utilized as a tool for the large-scale purification of lactate dehydrogenase and related enzymes. This is crucial for the development of drugs targeting these enzymes, as well as for the production of enzyme-based therapeutics. The selective and efficient purification process ensures the quality and purity of the enzymes, which is essential for their safe and effective use in medical applications.
Used in Diagnostic Applications:
Oxamate-diaminohexyl-sepharose is employed as a component in diagnostic assays and kits for the detection and quantification of lactate dehydrogenase and related enzymes. The specific binding properties of the compound enable the accurate measurement of enzyme levels in biological samples, which can be indicative of certain diseases or conditions. This aids in the diagnosis and monitoring of various health issues, contributing to better patient care and treatment outcomes.
Used in Enzyme Production:
Oxamate-diaminohexyl-sepharose is used as a purification agent in the production of lactate dehydrogenase and other enzymes for industrial applications. oxamate-diaminohexyl-sepharose's ability to selectively bind and purify these enzymes from complex mixtures ensures a high level of purity and activity, which is necessary for their use in various industrial processes, such as biocatalysis, food processing, and the production of biotechnological products.

Check Digit Verification of cas no

The CAS Registry Mumber 76082-51-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,0,8 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 76082-51:
(7*7)+(6*6)+(5*0)+(4*8)+(3*2)+(2*5)+(1*1)=134
134 % 10 = 4
So 76082-51-4 is a valid CAS Registry Number.

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