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760903-26-2

N-[4-(3-Thienyl)-1,3-thiazol-2-yl]guanidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 760903-26-2 Structure

  • Basic information

    1. Product Name: N-[4-(3-Thienyl)-1,3-thiazol-2-yl]guanidine
    2. Synonyms: N-[4-(3-Thienyl)-1,3-thiazol-2-yl]guanidine;N-(4-Thiophen-3-yl-thiazol-2-yl)-guanidine
    3. CAS NO:760903-26-2
    4. Molecular Formula: C8H8N4S2
    5. Molecular Weight: 224.30592
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 760903-26-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-[4-(3-Thienyl)-1,3-thiazol-2-yl]guanidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-[4-(3-Thienyl)-1,3-thiazol-2-yl]guanidine(760903-26-2)
    11. EPA Substance Registry System: N-[4-(3-Thienyl)-1,3-thiazol-2-yl]guanidine(760903-26-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 760903-26-2(Hazardous Substances Data)

760903-26-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 760903-26-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,0,9,0 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 760903-26:
(8*7)+(7*6)+(6*0)+(5*9)+(4*0)+(3*3)+(2*2)+(1*6)=162
162 % 10 = 2
So 760903-26-2 is a valid CAS Registry Number.

760903-26-2Relevant articles and documents

Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents

Li, Wen-Tai,Hwang, Der-Ren,Song, Jen-Shin,Chen, Ching-Ping,Chen, Tung-Wei,Lin, Chi-Hung,Chuu, Jiunn-Jye,Lien, Tzu-Wen,Hsu, Tsu-An,Huang, Chen-Lung,Tseng, Huan-Yi,Lin, Chu-Chung,Lin, Heng-Liang,Chang, Chung-Ming,Chao, Yu-Sheng,Chen, Chiung-Tong

scheme or table, p. 164 - 175 (2012/06/01)

Designed from a high throughput screened hit compound, novel 2-amino-1-thiazolyl imidazoles were synthesized and demonstrated cytotoxicity against human cancer cells. 1-(4-Phenylthiazol-2-yl)-4-(thiophen-2-yl)- 1Himidazol- 2-amine (compound 2), a 2-amino-1-thiazolyl imidazole, inhibited tubulin polymerization, interacted with the colchicine-binding sites of tubulins, and caused cell cycle arrest at the G2/M phase in human gastric cancer cells. Disruption of the microtubule structure in cancer cells by compound 2 was also observed. Compound 2 concentration-dependently inhibited the proliferation of cancer cells in histocultured human gastric and colorectal tumors. Given orally, compound 2 prolonged the lifespans of leukemia mice intraperitoneally inoculated with the murine P388 leukemic cells. We report 2-amino-1-thiazolyl imidazoles as a novel class of orally active microtubuledestabilizing anticancer agents. Springer Science+Business Media, LLC 2010.

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