760966-07-2

Upstream product

• 103082-82-2 phenyl 3-O-benzyl-4,6-O-benzylidene-β-D-glucopyranoside 
• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 108-24-7 acetic anhydride 

Downstream Products

• 760966-08-3 phenyl 3-O-benzyl-6-O-tosyl-2-O-triisopropylsilyl-β-D-glucopyranoside 
• 760966-09-4 phenyl 6-azido-6-deoxy-3-O-benzyl-2-O-triisopropylsilyl-β-D-glucopyranoside 
• 760966-13-0 phenyl 6-azido-6-deoxy-3-O-benzyl-4-O-methyl-2-O-triisopropylsilyl-β-D-glucopyranoside 
• 760966-15-2 phenyl 6-azido-6-deoxy-3-O-benzyl-4-O-isobutyl-2-O-triisopropylsilyl-β-D-glucopyranoside 
• 760966-14-1 phenyl 6-azido-6-deoxy-3-O-benzyl-4-O-propyl-2-O-triisopropylsilyl-β-D-glucopyranoside 
• 760966-16-3 phenyl 6-azido-6-deoxy-3,4-di-O-benzyl-2-O-triisopropylsilyl-β-D-glucopyranoside 
• 760966-10-7 phenyl 6-(N-tert-butoxycarbonylvalinyl)amino-6-deoxy-3-O-benzyl-4-O-methyl-2-O-triisopropylsilyl-β-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of peptidomimetics based on iminosugar and β-D- glucopyranoside scaffolds and inhibiton of HIV-protease

Synthetic routes to peptidomimetic compounds derived from saccharide scaffolds are described. The regioselective introduction of pivaloyl groups was achieved from N-benzyloxycarbonyl protected 1-deoxymannojirimycin or via D-fructopyranosides. The results from biological evaluation of the saccharide derivatives as HIV-protease inhibitors are included.