760981-77-9

Upstream product

• 760981-73-5 11-N-(4-azidobutyl)-6-O-methyl-5-hydroxy-3-oxoerythronolide A 11,12-carbamate 
• 849407-76-7 (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-1-(4-Azido-butyl)-10-((2S,4S,6R)-4-dimethylamino-6-methyl-3-oxo-tetrahydro-pyran-2-yloxy)-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-octahydro-3,5-dioxa-1-aza-cyclopentacyclotetradecene-2,6,8,14-tetraone 
• 760981-81-5 11-N-(4-azido-butyl)-6-O-methyl-5-(2-acetyl-desosamynyl)-3-oxo-erythronolide A 11,12-carbamate 
• 849407-75-6 11-N-(4-azido-butyl)-6-O-methyl-5-O-desosaminyl-3-oxo-erythronolide A 11,12-carbamate 
• 217977-00-9 10,11-anhydro-2',4''-di-O-acetyl-12-O-(imidazol-1-ylcarbonyl)-6-O-methylerythromycin A 
• 849407-72-3 C₅₄H₈₆N₂O₁₈S 
• 849407-73-4 C₄₇H₇₉N₅O₁₅ 
• 849407-71-2 C₄₇H₈₀N₂O₁₆ 
• 849407-74-5 acetic acid 2-[1-(4-azido-butyl)-4-ethyl-8-hydroxy-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,14-trioxo-tetradecahydro-3,5-dioxa-1-aza-cyclopentacyclotetradecen-10-yloxy]-4-dimethylamino-6-methyl-tetrahydro-pyran-3-yl ester 
• 760981-72-4 1-(4-azido-butyl)-10-(4-dimethylamino-3-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-4-ethyl-8-hydroxy-11-methoxy-3a,7,9,11,13,15-hexamethyl-decahydro-3,5-dioxa-1-aza-cyclopentacyclotetradecene-2,6,14-trione 

Downstream Products

• 849407-82-5 C₄₇H₆₃N₅O₁₃ 

Relevant academic research and scientific papers

Antibacterial agents

Described herein are novel macrolides, the preparation of novel macrolides, the use of novel macrolides for preventing, treating, or ameliorating various conditions, and the use of novel macrolides as antibacterial agents.

An efficient entry to new sugar modified ketolide antibiotics

A new and efficient route to a ketolide aglycon served as a basis for the unprecedented 5-O-glyco-modification of ketolide antibiotics. Combined with an effective copper-catalyzed triazole-forming reaction a series of novel and potent ketolide antibiotics

Synthesis and biological activity of new 5-O-sugar modified ketolide and 2-fluoro-ketolide antibiotics

A series of new triazole-containing ketolides and 2-fluoro-ketolides in which the 5-O-desosamine was replaced by unnatural sugars were synthesized and evaluated against relevant macrolide-sensitive and macrolide-resistant respiratory pathogens. Excellent