760989-91-1 Usage
Description
4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl-4-ol is an organic compound with the chemical formula C20H21BO3. It is a derivative of biphenyl and contains a boron atom in its structure. 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl-4-ol is characterized by its unique molecular structure, which features a 1,3,2-dioxaborolane moiety attached to a biphenyl-4-ol core. Its presence as a building block in the synthesis of complex organic molecules makes it a valuable compound in chemical and pharmaceutical research.
Used in Chemical Research:
4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl-4-ol is used as a synthetic building block for the creation of other complex organic molecules. Its unique structure allows for versatile chemical reactions and modifications, making it a valuable component in the development of new compounds with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl-4-ol is used as a key intermediate in the synthesis of pharmaceutically active compounds. Its ability to be modified and incorporated into larger molecular structures makes it a promising candidate for the development of new drugs and therapeutic agents.
Used in Organic Light-Emitting Diodes (OLEDs):
4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl-4-ol is used as a component in the development of organic light-emitting diodes (OLEDs). Its electronic properties and structural features make it suitable for use in the design and fabrication of OLED devices, which have applications in display technologies and lighting.
Used in Materials Science:
In the field of materials science, 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl-4-ol is used for the design and synthesis of new functional materials. The presence of the boron atom in its structure contributes to its versatility, allowing for the creation of materials with unique properties and potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 760989-91-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,0,9,8 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 760989-91:
(8*7)+(7*6)+(6*0)+(5*9)+(4*8)+(3*9)+(2*9)+(1*1)=221
221 % 10 = 1
So 760989-91-1 is a valid CAS Registry Number.
760989-91-1Relevant articles and documents
Compound with AMPK agonistic activity and preparation and application of prodrug thereof
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Paragraph 0145; 0149-0150; 0289; 0293-0294, (2021/10/27)
The invention relates to a compound with AMPK agonistic activity and a prodrug thereof, and as well as a preparation method and medical application of a prodrug thereof. The compound has the structure shown in the formula (I), and the prodrug of the compound has the structure shown in the formula (II), wherein each group and the substituent are as defined in the specification. The invention discloses a preparation method of the compound and application of the compound in prevention and treatment AMPK related diseases, and the AMPK related diseases include, but are not limited to, energy metabolism abnormality related diseases. Neurodegenerative diseases and inflammation-related diseases and the like.
Phenolic Bis-styrylbenzo[ c]-1,2,5-thiadiazoles as Probes for Fluorescence Microscopy Mapping of Aβ Plaque Heterogeneity
Zhang, Jun,Konsmo, Audun,Sandberg, Alexander,Wu, Xiongyu,Nystr?m, Sofie,Obermüller, Ulrike,Wegenast-Braun, Bettina M.,Konradsson, Peter,Lindgren, Mikael,Hammarstr?m, Per
, p. 2038 - 2048 (2019/02/26)
A fluorescent bis-styryl-benzothiadiazole (BTD) with carboxylic acid functional groups (X-34/Congo red analogue) showed lower binding affinity toward Aβ1-42 and Aβ1-40 fibrils than its neutral analogue. Hence, variable patterns of neutral OH-substituted bis-styryl-BTDs were generated. All bis-styryl-BTDs showed higher binding affinity to Aβ1-42 fibrils than to Aβ1-40 fibrils. The para-OH on the phenyl rings was beneficial for binding affinity while a meta-OH decreased the affinity. Differential staining of transgenic mouse Aβ amyloid plaque cores compared to peripheral coronas using neutral compared to anionic bis-styryl ligands indicate differential recognition of amyloid polymorphs. Hyperspectral imaging of transgenic mouse Aβ plaque stained with uncharged para-hydroxyl substituted bis-styryl-BTD implicated differences in binding site polarity of polymorphic amyloid plaque. Most properties of the corresponding bis-styryl-BTD were retained with a rigid alkyne linker rendering a probe insensitive to cis-trans isomerization. These new BTD-based ligands are promising probes for spectral imaging of different Aβ fibril polymorphs.
FUSED TRI AND TETRA-CYCLIC PYRAZOLE KINASE INHIBITORS
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Page 62; 85, (2010/02/08)
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