76112-81-7Relevant academic research and scientific papers
Synthesis and Biological Evaluation of Novel Dispiro Compounds based on 5-Arylidenehydantoins and Isatins as Inhibitors of p53–MDM2 Protein–Protein Interaction
Beloglazkina, Anastasia,Barashkin, Alexander,Polyakov, Vladislav,Kotovsky, German,Karpov, Nikita,Mefedova, Sofia,Zagribelny, Bogdan,Ivanenkov, Yan,Kalinina, Marina,Skvortsov, Dmitry,Tafeenko, Victor,Zyk, Nikolay,Majouga, Alexander,Beloglazkina, Elena
, p. 747 - 755 (2020/07/30)
[Figure not available: see fulltext.] A series of novel hydantoin-based dispiroindolinones as potential small-molecule inhibitors of p53–MDM2 protein–protein interaction were synthesized by two methods, using 2-arylidenehydantoins as starting materials. S
INTRODUCTION OF SELENIUM INTO HETEROCYCLIC COMPOUNDS. PART I. SYNTHESIS OF 3-ARYL-2-SELENOHYDANTOINS WITH DOUBLE BOND AT C-5
Korohoda, Maria Jolanta
, p. 683 - 692 (2007/10/02)
A new method of synthesis of so far unknown 3-aryl-5-chlorobenzylidene-2-selenohydantoins has been described.The reaction is based on substitution of the thiomethyl group by selenium in appropriate derivatives of 2-thiohydantoin.The structure of the produ
