76116-33-1

Upstream product

• 50619-36-8 2,3,5-tri-Obenzyl-α,β-D-ribofuranosylchloride 
• 10160-87-9 Propiolaldehyde diethyl acetal 
• 75155-97-4 (2R,3R,4S)-1,3,4-Tris-benzyloxy-8,8-diethoxy-oct-6-yne-2,5-diol 
• 69309-71-3 3,3-diethoxyprop-1-ynylmagnesium bromide 
• 16838-89-4 2,3,5-tri-O-benzyl-D-ribofuranose 

Downstream Products

• 76227-53-7 3(5)-(2,3,5-tri-O-benzyl-α-D-ribofuranosyl)pyrazole 
• 76227-52-6 1-(2,4-dinitrophenyl)-3-(2,3-O-isopropylidene-α-D-ribofuranosyl)pyrazole 
• 76227-51-5 1-(2,4-dinitriphenyl)-3-(2,3,5-tri-O-benzyl-α-D-ribofuranosyl)pyrazole 
• 76227-54-8 (2R,3R,4S,5R)-2-[1-(2,4-Dinitro-phenyl)-1H-pyrazol-3-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

Relevant academic research and scientific papers

C-Nucleoside Studies. Part 10. A New Synthesis of 3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)pyrazole and its Conversion into 4-Nitro-3(5)-β-D-ribofuranosylpyrazole

1,1-Diethoxy-3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)prop-2-yne (12) has been synthesised from 2,3,5-tri-O-benzyl-D-ribofuranose in 52percent yield.Acidic hydrolysis followed by reaction with hydrazine affords 3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)pyraz

A New Synthesis of Formycin via Nitropyrazole Derivatives

3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)pyrazole (4) has been converted into formycin (15) by a sequence involving, as the key step, cine substitution, by cyanide ion, of the 1-nitro group in the 1,4-dinitro-pyrazole (10).

C-Nucleoside Studies. Part 9. Synthesis of 3(5)-α-D-Ribofuranosylpyrazole and Related Compounds

3-(1,2:4,5-Di-O-isopropylidene-D-allo-1,2,3,4,5-pentahydroxypentyl)-1-(2,4-dinitrophenyl)pyrazole (8) was prepared in four steps (40percent overall yield) from 2,3:5,6-di-O-isopropylidene-D-allose (4).Treatment of (8) with acetone and concentrated sulphur