76129-16-3 Usage
Uses
Used in Pharmaceutical Industry:
Acetamide, 2,2,2-trifluoro-N-[5,6,7,9-tetrahydro-1,2, 3-trimethoxy-10(methylthio)-9-oxobenzo[a]heptalen-7-yl]-, (S)is used as a pharmaceutical intermediate for the development of new drugs due to its unique structure and potential biological activity.
Used in Biochemical Research:
Acetamide, 2,2,2-trifluoro-N-[5,6,7,9-tetrahydro-1,2, 3-trimethoxy-10(methylthio)-9-oxobenzo[a]heptalen-7-yl]-, (S)is utilized in biochemical research to study its interactions with various biological targets and to explore its potential as a therapeutic agent for various diseases.
Used in Chemical Synthesis:
Acetamide, 2,2,2-trifluoro-N-[5,6,7,9-tetrahydro-1,2, 3-trimethoxy-10(methylthio)-9-oxobenzo[a]heptalen-7-yl]-, (S)serves as a key building block in the synthesis of more complex molecules with potential applications in various fields, including materials science and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 76129-16-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,1,2 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 76129-16:
(7*7)+(6*6)+(5*1)+(4*2)+(3*9)+(2*1)+(1*6)=133
133 % 10 = 3
So 76129-16-3 is a valid CAS Registry Number.
InChI:InChI=1/C22H22F3NO5S/c1-29-16-9-11-5-7-14(26-21(28)22(23,24)25)13-10-15(27)17(32-4)8-6-12(13)18(11)20(31-3)19(16)30-2/h6,8-10,14H,5,7H2,1-4H3,(H,26,28)/t14-/m0/s1
76129-16-3Relevant academic research and scientific papers
Synthesis an Biological Effects of Novel Thiocolchicines. 3. Evaluation of N-Acyldeacetylthiocolchicines, N-(Alkoxycarbonyl)deacetylthiocolchicines, and O-Ethyldemethylthiocolchicines. New Synthesis of Thiodemecolcine and Antileukemic Effects of 2-Demethy
Kerekes, Peter,Sharma, Padam N.,Brossi, Arnold,Chignell, Colin F.,Quinn, Frank R.
, p. 1204 - 1208 (2007/10/02)
Novel and known analogues of thiocolchicine were evaluated in a tubulin binding assay in vivo in mice for acute toxicity and in the P338 lymphocytic leukemia assay.This evaluation included N-acyldeacetylthiocolchicines, N-(alkoxycarbonyl)deacetylthiocolch
Quantitative Structure-Activity Relationships of Colchicines against P388 Leukemia in Mice
Quinn, Frank R.,Beisler, John A.
, p. 251 - 256 (2007/10/02)
A quantitative structure-activity relationship (QSAR) was derived for colchicine and 14 analogues acting against P388 lymphocytic leukemia in mice.Twelve additional compounds were synthesized to reinforce and confirm the correlation.The final correlation
