761381-55-9Relevant academic research and scientific papers
A two-step synthesis of cytostatically active benzo[c]phenanthridine derivatives
Clement, Bernd,Weide, Matthias,Wolschendorf, Ulrich,Kock, Ilka
, p. 635 - 638 (2005)
Lots, fast: Benzo[c]phenanthridine derivatives are prepared efficiently by the reaction of aldehydes and 2-methylbenzonitrile in the presence of potassium tert-butanolate, followed by dehydration (see scheme). Some of these compounds demonstrate excellent
Synthesis and biological evaluation of 11-substituted 6-aminobenzo[c] phenanthridine derivatives, a new class of antitumor agents
Kock, Ilka,Heber, Dieter,Weide, Matthias,Wolschendorf, Ulrich,Clement, Bernd
, p. 2772 - 2777 (2007/10/03)
The synthesis of 11-substituted 6-amino-11,12-dihydrobenzo[c] phenanthridines and 11-substituted 6-aminobenzo[c]phenanthridines through an efficient method is described. The antiproliferative activity of selected compounds against a wide panel of tumor ce
