76143-80-1

Basic information

• Product Name: (2,2-Diethoxy-ethyl)-[1-(3-methoxy-phenyl)-propyl]-amine
• CAS NO: 76143-80-1
• Molecular Weight: 281.395
• Mol File: 76143-80-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2,2-Diethoxy-ethyl)-[1-(3-methoxy-phenyl)-propyl]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2-Diethoxy-ethyl)-[1-(3-methoxy-phenyl)-propyl]-amine(76143-80-1)
• EPA Substance Registry System: (2,2-Diethoxy-ethyl)-[1-(3-methoxy-phenyl)-propyl]-amine(76143-80-1)

Safety Data

• Hazardous Substances Data: 76143-80-1(Hazardous Substances Data)

Upstream product

• 925-90-6 ethylmagnesium bromide 
• 61190-04-3 (2,2-Diethoxy-ethyl)-[1-(3-methoxy-phenyl)-meth-(Z)-ylidene]-amine 

Relevant articles and documents

A ONE-POT ISOQUINOLINE SYNTHESIS BY CYCLODEHYDROGENATION OF BENZYLAMINOACETALS WITH CHLOROSULFONIC ACID

A direct preparation of the fully aromatized isoquinolines (3a-l) by the cyclodehydrogenation of benzylamnoacetals (2a-l) with chlorosulfonic acid is described.Comparing the behavior of chlorosulfonic acid with that of sulfuric acid toward 1,2-dihydroisoquinoline, it is able to be suggested that benzylaminoacetals were cyclized first to 1,2-dihydroisoquinolines, subsequently, dehydrogenated to the fully aromatized isoquinolines by the hydride abstraction with ClSO3H.Subtitution by a larger R3 group than isopropyl in the acetal ArCH(R3)NHCH2CH(OEt)2, interfered this second step, so the corresponding isoquinolines could not be obtained.