761440-39-5

Usage

Uses

Used in Pharmaceutical Industry:
[1-(3-Methoxy-4-nitro-phenyl)-piperidin-4-yl]-Methyl-carbaMic acid tert-butyl ester is used as a potential candidate in the pharmaceutical industry for its complex molecular structure that may offer novel interactions with biological targets, potentially leading to the development of new therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, [1-(3-Methoxy-4-nitro-phenyl)-piperidin-4-yl]-Methyl-carbaMic acid tert-butyl ester can be utilized as a building block or intermediate for the synthesis of more complex molecules, contributing to the advancement of chemical libraries and the discovery of new compounds with specific applications.
Used in Medicinal Chemistry:
[1-(3-Methoxy-4-nitro-phenyl)-piperidin-4-yl]-Methyl-carbaMic acid tert-butyl ester may serve as a valuable compound in medicinal chemistry, where its unique structure could be exploited to design and optimize new drugs with improved pharmacological profiles, targeting various diseases and conditions.

Upstream product

• 1356962-89-4 tert-butyl (1-(3-methoxy-4-nitrophenyl)piperidin-4-yl)carbamate 
• 74-88-4 methyl iodide 

Relevant academic research and scientific papers

N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER

The present invention relates to a N2,N4-diphenylpyrimidin-2,4-diamine derivative, a method for preparing the same, and a pharmaceutical composition for the prevention or treatment of cancer, containing the same as an active ingredient. The derivative sho

ALK (anaplastic lymphoma kinase) protein degradation agent and anti-tumor application thereof

The invention discloses a compound in a formula (I) and an anti-tumor application thereof. The compound in the formula (I) has degradation and inhabitation functions on ALK target protein and mainly comprises four parts, the first part ALK-TKIs is a compound with ALK tyrosine kinase inhabitation activity; the second part LIN is different linkers; the third part ULM (ubiquitin ligase binding moiety) of VHL, CRBN or other protease micromolecular ligand with a ubiquitination function; the fourth part group A is carboxyl or deficiency and covalently binds ALK-TKIs with LIN and covalently binds LINwith ULM. A series of designed and synthesized compounds have wide pharmacological activity, have functions of degrading ALK protein and inhibiting ALK activity and can be applied to related tumor therapy.

CHEMICAL COMPOUNDS

The present invention relates to compounds of Formula (I) and/or Formula (Ia): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit ALK kinase activity, and thus may be used for the tr

2, 4- DI (PHENYLAMINO) PYRIMIDINES USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES, INFLAMMATORY AND IMMUNE SYSTEM DISORDERS

Novel pyrimidine derivatives of formula (I), to processes for their production, their use as pharmaceuticals in the treatment of neoplastic diseases, inflammatory and immune system disorders and to pharmaceutical compositions comprising them.