761457-24-3

Usage

Type of compound

Heterocyclic compound

Structural components

Piperidine ring, thioxo group, and methyl ester group

Derivative

Methyl ester derivative of 2-thioxo-1-piperidinecarboxylic acid

Usage

Reagent in organic synthesis, building block for pharmaceuticals and agrochemicals

Safety precautions

Toxic or irritating effects, should be handled with care, used in well-ventilated areas, and proper protective equipment should be worn.

Upstream product

• 13070-01-4 piperidine-2-thione 
• 79-22-1 methyl chloroformate 
• 675-20-7 piperidin-2-one 

Relevant academic research and scientific papers

An efficient synthesis of chiral cyclic β-amino acids via asymmetric hydrogenation

Cyclic β-amino acids, homoproline, homopipecolic acid and 3-carboxy-methylmorpholine were obtained in high enantiomeric excesses by transition metal-catalyzed asymmetric hydrogenation of cyclic β-acylamino-alkenoates. These compounds were synthesized by a

PROCESS FOR THE ENANTIOSELECTIVE PRODUCTION OF AN AMINO ACID DERIVATIVE COMPRISING AT LEAST ONE NITROGENOUS HETEROCYCLE

Process for the enantioselective production of an amino acid derivative comprising at least one nitrogenous heterocycle, said heterocycle being substituted with at least one side chain comprising a functional group of carboxyl type, such as a carboxyl group, an ester group or an amide group, which process comprises at least one step in which a prochiral unsaturated amino acid derivative of formula (I) is subjected to hydrogenation in the presence of an enantiopure hydrogenation catalyst.