76152-22-2

Basic information

• Product Name: N-dodecyl-Nα-(6-bromohexanoyl)-O-benzyl-L-aspartamide
• Synonyms: N-dodecyl-Nα-(6-bromohexanoyl)-O-benzyl-L-aspartamide
• CAS NO: 76152-22-2
• Molecular Weight: 567.607
• Mol File: 76152-22-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-dodecyl-Nα-(6-bromohexanoyl)-O-benzyl-L-aspartamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-dodecyl-Nα-(6-bromohexanoyl)-O-benzyl-L-aspartamide(76152-22-2)
• EPA Substance Registry System: N-dodecyl-Nα-(6-bromohexanoyl)-O-benzyl-L-aspartamide(76152-22-2)

Safety Data

• Hazardous Substances Data: 76152-22-2(Hazardous Substances Data)

Upstream product

• 22809-37-6 6-bromohexanoyl chloride 
• 76152-21-1 (S)-3-Amino-N-dodecyl-succinamic acid benzyl ester; compound with trifluoro-acetic acid 

Downstream Products

• 76152-23-3 N-dodecyl-Nα-(6-trimethylammoniohexanoyl)-O-benzyl-L-aspartamide bromide 

Relevant articles and documents

Aggregation Behaviour of Synthetic Peptide Surfactants

Single-chain surfactants with an amino-acid residue as part of a hydrophobic chain, SS'-bis-α-(6-trimethylammoniohexanoyl)-L-hemicysteinamide> bromide +C5CysC12)2>, N-dodecyl-Nα-(6-trimethylammoniohexanoyl)-S-benzyl-L-cysteinamide bromide +C5Cys(Bzl)C12>, and N-dodecyl-Nα-(6-trimethylammoniohexanoyl)-L-aspartamide bromide (N+C5AspC12) have been synthesized and the structures of the aggregates formed in aqueous media investigated.The peptide surfactants form tighter aggregates than ordinary micelles formed with octadecyltrimethylammonium chloride.The weight-average molecular weights of the aggregates in aqueous media were determined by the low angle laser light scattering technique: N+C5Cys(Bzl)C12, 7.04*1E6; (N+C5CysC12)2, 1.49*1E6; N+C5AspC12, 5.06*1E4.Consequently, N+C5AspC12 forms tight spherical micelles while (N+C5CysC12)2 and N+C5(Bzl)C12 constitute tight and large cylindrical micelles.This aggregation behaviour was also confirmed by elctronmicroscopy.The introduction of an amino-acid residue into the hydrophobic chain of a surfactant result in tightening of the aggregate structure in aqueous media, probably due to intermolecular hydrogen bonding among amino-acid moieties in the micelle.