76156-40-6

Basic information

• Product Name: (+/-)-(1R,2S)-2-[(Z)-1-propenyl]cyclohexanol
• Synonyms: (+/-)-(1R,2S)-2-[(Z)-1-propenyl]cyclohexanol
• CAS NO: 76156-40-6
• Molecular Weight: 140.225
• Mol File: 76156-40-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (+/-)-(1R,2S)-2-[(Z)-1-propenyl]cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-(1R,2S)-2-[(Z)-1-propenyl]cyclohexanol(76156-40-6)
• EPA Substance Registry System: (+/-)-(1R,2S)-2-[(Z)-1-propenyl]cyclohexanol(76156-40-6)

Safety Data

• Hazardous Substances Data: 76156-40-6(Hazardous Substances Data)

Upstream product

• 590-15-8 trans-2-propenyl bromide 
• 286-20-4 cyclohexane-1,2-epoxide 
• 590-13-6 (Z)-1-propenyl bromide 
• 2277-20-5 (E)-non-6-enal 
• 1184-58-3 dimethylaluminum chloride 

Relevant articles and documents

Highly regioselective copper-catalyzed cis- and trans-1-propenyl Grignard cleavage of hindered epoxides. Application in propionate synthesis

Hindered protected and unprotected epoxy alcohols were regioselectively cleaved using copper-catalyzed cis- and trans-1-propenylmagnesium bromide. The reaction exhibited good yield and excellent regioselectivity in systems where organocuprates and organoalanes failed. The cis Grignard reagent displayed no double-bond isomerization, whereas the trans isomer showed partial trans-to-cis equilibration, which was minimized by controlling the reagent formation conditions. The reaction was shown to be highly useful for the elaboration of the C10-C15 Streptovaricin D ansa chain fragment.

Alkylaluminium Chloride Induced Cyclization of Unsaturated Carbonyl Compounds

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