76170-28-0

Basic information

• Product Name: 3-piperidinocyclobutane-1-carbonitrile
• CAS NO: 76170-28-0
• Molecular Weight: 164.25
• Mol File: 76170-28-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-piperidinocyclobutane-1-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-piperidinocyclobutane-1-carbonitrile(76170-28-0)
• EPA Substance Registry System: 3-piperidinocyclobutane-1-carbonitrile(76170-28-0)

Safety Data

• Hazardous Substances Data: 76170-28-0(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 16955-35-4 1-cyanobicyclo<1.1.0>butane 
• 76170-31-5 3-piperidinocyclobutane-1-carbonitrile 

Relevant articles and documents

Addition to bicyclobutane derivatives. IV. Stereochemistry of the addition of secondary amines to bicyclobutane-1-carbonitrile and 3-methylbicyclobutane-1-carbonitrile

Secondary amines (dimethylamine, diethylamine, pyrrolidine, piperidine, and morpholine) add to bicyclobutane-1-carbonitrile and 3-methylbicyclobutane-1-carbonitrile exclusively at the central C-C bond with nucleophilic attack at the β position in relation to the nitrile group.The reactions are not stereospecific, but they are all cis-stereoselective.It was found that the structure of the substrate and the reagent and also the nature of the solvent have effects on the stereochemistry of addition.