76179-41-4

Upstream product

• 78056-39-0 4,5-difluoro-2-nitroaniline 
• 76179-40-3 2-amino-4,5-difluoroaniline 
• 609-09-6 Diethyl ketomalonate 
• 59743-08-7 diethyl 2,3-dioxosuccinate 

Relevant academic research and scientific papers

Synthesis of substituted 2-ethoxycarbonyl- and 2-carboxyquinoxalin -3 ones for evaluation of antimicrobial and anticancer activity

A series of variously substituted quinoxalin-3-ones bearing an ethoxycarbonyl or carboxy group in the C-2 position has been prepared and their structures proved by 1H NMR spectroscopy. The obtained compounds were investigated in vitro for antimicrobial and anticancer activities. Preliminary results showed a moderate activity against a few strains of bacteria but no significant anticancer and anti-HIV activity.

Salts of dihalo-3,4-dihydro-3-oxo-2-quinoxaline carboxylic acids and hindered amines

Salts of 6,7-dihalo-3,4-dihydro-3-oxo-2-quinoxaline carboxylic acids and hindered amines, useful in combating influenza A and B.

Treatment of influenza with 2-estersubstituted-3,4-dihydro-3-oxoquinoxalines

3,4-Dihydro-3-oxoquinoxalines carrying a carboxylic acid or ester function in the 2 position, used as antiviral agents, particularly against influenza virus, both A and B strains.