76180-97-7Relevant academic research and scientific papers
1-Aza-1',3'-diaza-3,3'-sigmatropic rearrangements - A convenient synthesis of benzimidazole derivatives
Teresa,Carvalho,Lobo, Ana M.,Branco, Paula S.,Prabhakar, Sundaresan
, p. 3115 - 3118 (2007/10/03)
1-Aryl-2-acyl-2-cyanohydrazines undergo smooth thermal rearrangements to provide 2-aminoacylbenzimidazoles in excellent yields. A short synthesis of the highly mutagenic dietary amine, IQ, is reported.
A Potent Mutagen in Broiled Fish. Part 1. 2-Amino-3-methyl-3H-imidazoloquinoline
Kasai, Hiroshi,Yamaizumi, Ziro,Nishimura, Susumu,Wakabayashi, Keiji,Nagao, Minako,at al.
, p. 2290 - 2293 (2007/10/02)
A potent mutagen isolated from a methanol extract of sardines broiled under normal domestic conditions was strongly mutagenic to Salmonella typhimurium TA98.Its identity has been established as 2-amino-3-methyl-3H-imidazoquinoline on the basis of spectral evidence and by chemical synthesis.
