76181-40-3

Basic information

• Product Name: Naphthalene, 4-chloro-1,2-dihydro-
• CAS NO: 76181-40-3
• Molecular Formula: C10H9Cl
• Molecular Weight: 164.634
• Mol File: 76181-40-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Naphthalene, 4-chloro-1,2-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: Naphthalene, 4-chloro-1,2-dihydro-(76181-40-3)
• EPA Substance Registry System: Naphthalene, 4-chloro-1,2-dihydro-(76181-40-3)

Safety Data

• Hazardous Substances Data: 76181-40-3(Hazardous Substances Data)

Upstream product

• 88920-84-7 (4,4-dichlorobut-3-en-1-yl)benzene 

Downstream Products

• 93-08-3 methyl 2-naphthyl ketone 

Relevant articles and documents

Friedel-crafts cyclization of 1,1-difluoroalk-1-enes: Synthesis of benzene-fused cyclic ketones via α-fluorocarbocations

1,1-Difluoroalk-1-enes bearing a phenyl group at the C-3, -4, or -5 position, readily obtained from 2,2,2-trifluoroethyl p-toluenesulfonate, are treated with FSO3H·SbF5 to undergo Friedel-Crafts cyclization in (CF3)2CHOH. The cyclization takes place via α-fluorocarbocations, followed by spontaneous hydrolysis of the C-F bond to afford bicyclic ketones including a five, six, or seven-membered ring in good yield.