76184-35-5

Upstream product

• 80179-08-4 Acetic acid (1S,4S)-4-hydroxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester 
• 73616-65-6 (+/-)-(1S,3S)-3-acetoxymethyl-1,2,2-trimethyl-1-vinylcyclopentane 
• 73616-73-6 Acetic acid (1S,4S)-4-bromomethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester 

Downstream Products

• 76231-58-8 ((1S,4S)-2,2,4-Trimethyl-3-methylene-cyclohexyl)-methanol 
• 76184-37-7 (3S,6S)-3-Methoxymethyl-2,2,6-trimethyl-cyclohexanone 
• 76184-36-6 (3S,6S)-6-Methoxymethyl-1,1,3-trimethyl-2-methylene-cyclohexane 

Relevant academic research and scientific papers

CHEMICAL TRANSFORMATION OF TERPENOIDS. II. ACID TREATMENT OF (3S)-1-VINYL-,(3S)-1-HYDROXYPROPENYL-, AND (3S)-1-EPOXYETHYL-1,2,2-TRIMETHYLCYCLOPENTANE DERIVATIVES: RING ENLARGEMENT REACTIONS AND SUCCESSIVE MIGRATIONS OF METHYL RESIDUES

Four 1,2,2-trimethylcyclopentane derivatives, (+)-(1S,3S)-3-acetoxymethyl-1,2,2-trimethyl-1-vinylcyclopentane (3), (+)-(1S,3S)-3-acetoxymethyl-1-(3'-hydroxypropenyl)-1,2,2-trimethylcyclopentane (4), (+)-(1R,3S,1'S)-3-acetoxymethyl-1-(1',2'-epoxyethyl)-1,2

SYNTHESIS OF A CHIRAL 1,1,3-TRIMETHYLCYCLOHEXANE DERIVATIVE FROM d-CAMPHOR: A POTENT KEY BUILDING BLOCK FOR ENT-TAXANE-TYPE DITERPENOIDS

A chiral 1,1,3-trimethylcyclohexane derivative (12), which is a potent key building block for synthesis of ent-taxane-type diterpenoids, has been prepared from d-camphor (2) through a conversion pathway which involves a novel ring enlargement reaction of a 1,1,2-trimethylcyclopentane derivative (3).