76202-82-9

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 17507-57-2 (diphenylphosphinyl)phenyldiazomethane 
• 71-43-2 benzene 
• 1499-21-4 Diphenylphosphinic chloride 
• 4559-70-0 Diphenylphosphine oxide 
• 92-29-5 hydrobenzamide 
• 76202-74-9 N,N'-Bis-[(diphenyl-phosphinoyl)-phenyl-methyl]-C-phenyl-methanediamine 

Relevant academic research and scientific papers

The organocatalytic enantiodivergent fluorination of β-ketodiaryl-phosphine oxides for the construction of carbon-fluorine quaternary stereocenters

Commercially available cinchona alkaloids that can catalyze the enantiodivergent fluorination of β-ketodiarylphosphine oxides were developed to construct carbon-fluorine quaternary stereocenters. This protocol features a wide scope of substrates and excellent enantioselectivities, and it is scalable.

Carbenes, 22. Phosphenes: Trapping Reactions of (Diphenylmethylene)phenylphosphane Oxide by -Cycloaddition with Aldehydes

The photolysis of (diazobenzyl)diphenylphosphane oxide (5) in benzene yields the short-lived (diphenylmethylene)phenylphosphane oxide (15) via the carbene 12.The heterocumulene is trapped by aromatic aldehydes, which are added to the reaction mixture, in a -cycloaddition reaction with formation of the 1,2λ5-oxaphosphetanes 16a-e.Carbene reactions with the solvent (formation of the norcaradiene 13) as well as with the trapping reagents (formation of the C/H-insertion products 10a and b) cannot be avoided.With the α,β-unsaturated aldehydes 22a-c, the 1,2λ5-oxaphosphetanes 23a-c are primarily formed.They undergo a complete or a partial photofragmentation to the 1,3-butadienes 24a-c and phenylphosphane dioxide (25).