76206-20-7

Upstream product

• 6373-46-2 p-benzyloxyaniline 
• 50-79-3 2,5-dichlorobenzoic acid 
• 4068-78-4 methyl 5-chloro-2-hydroxybenzoate 
• 104-94-9 4-methoxy-aniline 
• 857589-26-5 2-(N-benzoyl-p-anisidino)-5-chloro-benzoic acid methyl ester 

Downstream Products

• 815608-20-9 N-acetyl-sulfanilic acid-(2-chloro-7-methoxy-acridin-9-ylamide) 

Relevant academic research and scientific papers

Benzyl alcohol derivatives, their preparation and use

Novel hydroxyphenylaminobenzenealkanols, useful as antiasthmatic agents, are of the formula STR1 wherein R is hydrogen, lower-alkyl, lower-alkoxy or halo; R' is hydrogen or lower-alkyl; R" is hydrogen, lower-alkyl or halo; and Y is Cn H2n wherein n is 1-2. The compounds are prepared by de-etherification of the corresponding phenol alkyl or benzyl ethers; by reduction of the corresponding benzoic acids or esters thereof; or by reduction of ketones wherein --Y--OH is replaced by --COCH3.

Substituted aminobenzamides and their use as agents which inhibit lipoxygenase activity

Novel 2-(hydroxyphenylamino)benzamides and oxidation products thereof, useful as inhibitors of lipoxygenase, are of the formulas STR1 wherein R is hydrogen, lower-alkyl, halo or lower-alkoxy; R' is hydrogen or lower-alkyl; R" is hydrogen, lower-alkyl or halo; and N=Z is amino or substituted amino. The compounds of Formula I are prepared by de-etherification of the corresponding alkyl or benzyl ethers; and the compounds of Formula II are prepared by oxidation of the compounds of Formula I where R' is hydrogen and OH is in the 4-position.