76211-99-9Relevant academic research and scientific papers
Novel Heterocyclizations with Malonic Esters . 1,3-Dithioles; 1,3-Oxathioles; Δ2-Oxazolines and the Vinylene dipyridinium dication
Capuano, Lilly,Bronder, Marott,Hell, Wolfgang,Moersdorf, Peter,Hoge, Reinhold
, p. 899 - 908 (1980)
The reaction of diethyl bromomalonate (1) or diethyl diazomalonate (6) with benzoyl isothiocyanate (2) proceeds via the carbene intermediates 4,7 or 12 to afford the 1,3-dithiole 5, the Δ2-oxazoline 8 or the 1,3-oxathioles 9 depending upon the catalyst employed.In contrast, the bis(ethoxycarbonyl)methylpyridinium bromides 14 upon treatment with benzoyl isocyanates 15 in pyridine give rise to vinylene dipyridinium dibromides 18.- Keywords: Heterocyclizations; 1H-NMR-Spectroscopy; Iso(thio)cyanates; Malonates
