76217-58-8

Upstream product

• 73174-98-8 p-Nitrobenzyl (5R,6S)-3-(2-acetamidoethylthio)-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 76217-43-1 (5R,6S)-3-(2-Acetylamino-ethanesulfinyl)-6-((S)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 108-98-5 thiophenol 

Downstream Products

• 85431-75-0 (5R,6S)-6-((S)-1-Acetoxy-ethyl)-7-oxo-3-phenylsulfanyl-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 76217-89-5 (5R,6S)-6-((S)-1-Hydroxy-ethyl)-7-oxo-3-phenylsulfanyl-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 

Relevant academic research and scientific papers

2-Substituted thio carbapenem derivatives

A process for the preparation of an antibacterially active compound of the formula (I): STR1 and salts and esters thereof wherein R1 and R2 independently are hydrogen or an organic group, and R3 is an organic group bonded

VERSATILE CHEMICAL MODIFICATION OF THE C-2 SIDE CHAIN OF CARBAPENEM ANTIBIOTICS

Substitution of the C-2 side chain of carbapenem antibiotics with various types of sulfenyl groups was effected via carbapenem S-oxides by two ways.