7622-53-9Relevant academic research and scientific papers
Insect antifeedants, pterocarpans and pterocarpol, in heartwood of Pterocarpus macrocarpus Kruz
Morimoto, Masanori,Fukumoto, Hiromi,Hiratani, Masaru,Chavasiri, Warinthorn,Komai, Koichiro
, p. 1864 - 1868 (2006)
The insect antifeedant activities of pterocarpans and a sesquiterpene alcohol from the dichloromethane extract of Pterocarpus macrocarpus Kruz. (Leguminosae) were evaluated against the common cutworm, Spodoptera litura F. (Noctuidae), and the subterranean
Practical synthesis of lespedezol A1
Khupse, Rahul S.,Erhardt, Paul W.
, p. 275 - 277 (2008/12/23)
A practical formal synthesis of lespedezol A1 (1) was accomplished in 33% yield for four steps starting from formation of the substituted chalcone. Of particular note is a useful protocol for reduction of the 2-ene bond in the isoflavone intermediate. A significant improvement in the final ring closure when water was scavenged from the reaction is also noteworthy. The ready availability of lespedezol A1 will provide material for further pharmacological evaluation and for exploration of the pterocarpene nucleus as a potential entry into various 6a-hydroxypterocarpans.
A facile synthesis of biogenetic precursor, puerarone, isolated from Pueraria sp
Khan,Kapil
, p. 1007 - 1009 (2007/10/03)
Puerarone was synthesized using chalcone oxidation with thallium (III) trinitrate and chromenation of the resulting isoflavone using 3-hydroxyisovaleraldehyde dimethylacetal. The key demethylation step was achieved with boron tribromide.
Synthesis of (+/-)-Isomedicarpin, (+/-)-Homopterocarpin and Tuberostan: A Novel Entry of 'Hydrogenative Cyclisation' into Pterocarpans
Krishna Prasad, Awari V.,Kapil, Randhir S.,Popli, Satya P.
, p. 1561 - 1564 (2007/10/02)
An efficient three-step synthesis of the coumestan, tuberostan (1), from the benzyloxyisoflavone (2) is described.The synthesis involves a single-step 'hydrogenative cyclisation' of the isoflavone (2) to the pterocarpan, (+/-)-isomedicarpin (5).
