762252-31-3

Upstream product

• 762252-28-8 dimethyl 2-((1S,4R)-4-hydroxy-2-((tert-butyldimethylsilyloxy)methyl)cyclohex-2-enyl)-2-(3-(2-(tert-butyldimethylsilyloxy)ethyl)-1H-indol-2-yl)malonate 
• 762252-23-3 dimethyl 2-(3-(2-(tert-butyldimethylsilyloxy)ethyl)1H-indol-2-yl)malonate 
• 762252-37-9 dimethyl 2-(2-((Z)-3-(tert-butyldimethylsilyloxy)prop-1-enyl)phenylthiocarbamoyl)malonate 
• 762252-36-8 (Z)-(2-isothiocyanatocinnamyloxy)(tert-butyl)dimethylsilane 
• 762252-24-4 (((1S,6R)-7-oxa-bicyclo[4.1.0]hept-2-en-2-yl)methoxy)(tert-butyl)dimethylsilane 
• 762252-26-6 (5S,6S)-methyl 6-acetoxy-5-bromocyclohex-1-enecarboxylate 
• 762252-27-7 (1S,6S)-6-bromo-2-(hydroxymethyl)cyclohex-2-enol 
• 224315-42-8 2-[(1Z)-3-hydroxy-1-propenyl]phenylisothiocyanate 
• 5455-59-4 2-Nitrobenzenesulfonamide 
• 93-58-3 benzoic acid methyl ester 

Downstream Products

• 762252-32-4 (14R,14aR)-13-tert-butyl-14-methyl-1,2,3,5,6,7,8,14,14a-nonahydro-3-oxo-2-hydroxy-6-(2-nitrobenzenesulfonyl)benzo[7,8]azonino[5,4-b]indole-13,14(1H)-dicarboxylate 
• 762252-33-5 (10R,11R)-9-[1-Methoxycarbonyl-meth-(E)-ylidene]-7-(2-nitro-benzenesulfonyl)-10-(2-oxo-ethyl)-6,7,8,9,10,11-hexahydro-5H-7,12-diaza-cyclonona[a]indene-11,12-dicarboxylic acid 12-tert-butyl ester 11-methyl ester 

Relevant academic research and scientific papers

Total synthesis of (-)-strychnine

Total synthesis of (-)-strychnine is described. Notable features of our synthesis include (1) palladium-catalyzed coupling of the indole and vinyl epoxide moieties, (2) synthesis of the nine-membered cyclic amine derivative from the diol precursor in a one-pot procedure, and (3) transannular cyclization of the nine-membered cyclic amine. Copyright