76263-20-2Relevant academic research and scientific papers
3-Phenoxy-1-azetidinecarboxamides
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, (2008/06/13)
3-Phenoxy-1-azetidinecarboxamides having the formula STR1 wherein R1 is selected from the group consisting of hydrogen, fluoro, loweralkyl, loweralkoxy, trifluoromethyl, acetyl or aminocarbonyl having prolonged anticonvulsant activity are discl
Process for preparing 3-phenoxy-1-azetidines and carboxamide derivatives
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, (2008/06/13)
An improved process is disclosed for preparing 3-phenoxyazetidines which utilizes a phase transfer catalyst to add the phenoxy group to azetidine blocked in the 1-position by a diphenylmethane group and utilizes a stabilizing tertiary amine base to prevent dimerization during hydrogenolysis to remove the blocking group. The crude product containing diphenylmethane may be used without purification to prepare 3-phenoxy-1-azetidinecarboxamides.
N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides
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, (2008/06/13)
N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides having the formula: STR1 wherein R is selected from formyl and hydroxymethyl and R1 is selected from hydrogen, fluoro, loweralkyl, loweralkoxy, trifluoromethyl, acetyl, N-formylcarb
