76272-11-2Relevant academic research and scientific papers
3'-Arylspiro-3-ones and Their Conversion to 2-(3-Arylisoxazol-5-yl)benzoates
Liu, Kou-Chang,Howe, Robert K.
, p. 4590 - 4592 (2007/10/02)
A new, convenient route to the biologically active 2-(3-arylisoxazol-5-yl)benzoates 4 is reported.This route consists of 1,3-dipolar cycloaddition of aromatic nitrile oxides to 3-methylenephthalide to form the novel 3'-arylspiro-3-ones 3 and subsequent high-yield conversions of 3 to 4.
