76274-07-2Relevant academic research and scientific papers
One-pot preparation of azobenzenes from nitrobenzenes by the combination of an indium-catalyzed reductive coupling and a subsequent oxidation
Sakai, Norio,Asama, Shun,Anai, Satsuki,Konakahara, Takeo
, p. 2027 - 2033 (2014)
We demonstrated how a reduction step with a reducing system comprised of In(OTf)3 and Et3SiH and a subsequent oxidation that occurred under an ambient (oxygen) atmosphere allowed the highly selective and catalytic conversion of aromatic nitro compounds into symmetrical or unsymmetrical azobenzene derivatives. This catalytic system displayed a tolerance for the functional groups on a benzene ring: an alkyl group, a halogen, an acetyl group, an ester, a nitrile group, an acetyl group, an ester moiety, and a sulfonamide group.
