17β-Hydroxyestra-1,3,5(10)-trien-3-ol, also known as 17β-estradiol or simply estradiol, is a naturally occurring steroid hormone and the most potent form of estrogen. It plays a crucial role in the development of female secondary sexual characteristics, regulation of the menstrual cycle, and maintenance of pregnancy. Structurally, estradiol is composed of a steroid nucleus with a hydroxyl group at the 17β position and a double bond between carbons 1 and 2, as well as between carbons 4 and 5. This hormone is synthesized primarily in the ovaries, with additional production in the adrenal glands and, to a lesser extent, in the placenta during pregnancy. Estradiol is essential for bone health, cardiovascular function, and cognitive processes, and it has been the subject of extensive research due to its potential therapeutic applications in various conditions, including menopause, osteoporosis, and certain cancers.
The CAS Registry Mumber 7628-02-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,2 and 8 respectively; the second part has 2 digits, 0 and 2 respectively. Calculate Digit Verification of CAS Registry Number 7628-02: (6*7)+(5*6)+(4*2)+(3*8)+(2*0)+(1*2)=106 106 % 10 = 6 So 7628-02-6 is a valid CAS Registry Number.