76293-12-4

Upstream product

• 78500-68-2 bis-(3-bromopropyl) 2-acetamido-α-hydroxytriphenylmethane-4',4''-dicarboxylate 
• 78500-67-1 2-acetamido-4',4''-bis-(1,3-dioxan-2-yl)triphenylmethanol 
• 125716-40-7 4-(1,3-dioxan-2-yl)phenylmagnesium bromide 
• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 78500-72-8 dimethyl 2-amino-α-hydroxytriphenylmethane-4',4''-dicarboxylate 

Downstream Products

• 76293-06-6 dimethyl 2-azidotriphenylmethane-4',4''-dicarboxylate 

Relevant academic research and scientific papers

Intramolecular Nitrene Insertions into Aromatic and Heteroaromatic Systems. Part 7. Insertions into Electron-deficient Rings

A number of routes to o-aminotriphenylmethanes are described, where one benzene ring, or both, carry potential ester groups.The most useful synthon is shown to be the 1,3-dioxan-2-yl substituent, and using this methyl 2-aminodiphenylmethane-4'-carboxylate (18) and dimethyl 2-aminotriphenylmethane-4',4''-dicarboxylate (28) have been prepared.The azides from these, respectively (19) and (29), on thermolysis at 200 deg C gave azepinoindoles (48) and (51), the first examples of ring expansion by an arylnitrene of benzene rings with electron-withdrawing substituents.Also reported are syntheses of 3- and 4-(2-azidobenzyl)pyridines (38) and (39), and of 2-(2-azidobenzyl)thiazole (40); decomposition of these azides gave mainly polymers.