76293-62-4Relevant academic research and scientific papers
METHOD FOR PRODUCING OMEGA-HYDROXY FATTY ACID ESTER AND PRECURSOR COMPOUND THEREOF
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Paragraph 0099; 0100; 0102, (2016/07/27)
Provided is a method for producing a compound represented by Formula (III) while the production of by-products due to, for example, dimerization of a raw material or isomerization of a double bond position is suppressed. The method is a method for producing omega-hydroxy fatty acid ester and a precursor compound thereof of Formula (III), in which an alcohol derivative and a carboxylic acid derivative are subjected to a metathesis reaction in the presence of a catalyst to obtain a compound of Formula (III), wherein the alcohol derivative is at least one selected from the group consisting of a compound of Formula (VI) and a compound of Formula (I), and the carboxylic acid derivative is at least one selected from the group consisting of a compound of Formula (VII) and a compound of Formula (II), wherein the case where the alcohol derivative is formed of a compound of Formula (I) and the carboxylic acid derivative is formed of a compound of Formula (II) is excluded,
SYNTHESE DE MACROLIDES PAR METATHESE.
Villemin, Didier
, p. 1715 - 1718 (2007/10/02)
Two syntheses of macrolides via olefin metathesis are presented.The first (A) involves preparation of ω-hydroxyacid 6 or 9 by metathesis followed by cyclisation, while the second (B) involves macrocyclic ring closure by metathesis of a ω,ω'diunsaturated ester 12.
