76299-54-2Relevant academic research and scientific papers
Allergenic α-Methylene-γ-lactones. General Method for the Preparation of β-Acetoxy- and β-Hydroxy-α-methylene-γ-butyrolactones from Sulfoxides. Application to the Synthesis of a Tuliposide B Derivative
Corbet, Jean-Pierre,Benezra Claude
, p. 1141 - 1147 (2007/10/02)
A general synthesis of β-hydroxy-α-methylene-γ-butyrolactones , which is based on the sulfoxide-sulfenate rearrangement, is presented.Several β-acetoxy-α-methylene-γ-butyrolactones have been prepared and transformed into the β-hydroxy-derivatives through base hydrolysis.This synthesis has been applied to the first preparation of (tetraacetoxybenzyl)tuliposide B (22).
Synthesis and Antitumor Activity of Simple Vinyl and α-Methylene-γ-butyrolactone Sulfonate Esters and Silyl Enol Ethers
Stang, Peter J.,Treptow, Warren L.
, p. 468 - 472 (2007/10/02)
A number of simple silyl enol ethers and vinyl trifluoromethanesulfonates, a relatively new class of organic compounds capable of undergoing alkylation by a nucleophilic addition-elimination process, were evaluated in the P388 lymphocytic leukemia system.
