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Guanosine 5'-monophosphorothioate, also known as GMP-thio, is a modified nucleotide that features a sulfur atom in place of one of the non-bridging oxygen atoms in the phosphate group. This modification endows GMP-thio with distinctive properties, enabling it to engage in a range of chemical reactions that are not characteristic of unmodified nucleotides. Its stable structure and versatile reactivity make GMP-thio a valuable compound in the fields of biochemical research and pharmaceutical development.

76310-16-2

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76310-16-2 Usage

Uses

Used in Biochemistry and Molecular Biology Research:
GMP-thio is utilized as a research tool for studying RNA and DNA interactions, providing insights into the fundamental mechanisms of nucleic acid chemistry and biology.
Used in Pharmaceutical Development:
GMP-thio is employed as a component in the development of therapeutic agents targeting nucleic acids, potentially leading to novel treatments for various diseases.
Used in Chemical Reactions:
Due to its unique properties, GMP-thio is used as a reactant in a variety of chemical reactions that are not possible with standard nucleotides, expanding the scope of synthetic chemistry in the field of nucleic acid research.
Used in Drug Delivery Systems:
In the pharmaceutical industry, GMP-thio may be used as a component in drug delivery systems, potentially improving the efficacy and bioavailability of nucleic acid-based therapeutics.

Check Digit Verification of cas no

The CAS Registry Mumber 76310-16-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,3,1 and 0 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 76310-16:
(7*7)+(6*6)+(5*3)+(4*1)+(3*0)+(2*1)+(1*6)=112
112 % 10 = 2
So 76310-16-2 is a valid CAS Registry Number.

76310-16-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-9-[(2R,3R,4S,5R)-5-(dihydroxyphosphinothioyloxymethyl)-3,4-dihydroxyoxolan-2-yl]-3H-purin-6-one

1.2 Other means of identification

Product number -
Other names Guanosine 5'-monophosphorothioate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76310-16-2 SDS

76310-16-2Upstream product

76310-16-2Downstream Products

76310-16-2Relevant academic research and scientific papers

An improved synthesis of guanosine 5'-monothiophosphate

Behrman

, p. 446 - 447 (2007/10/03)

A synthesis of guanosine 5'-monothiophosphate which requires no chromatographic purification is described.

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