76337-97-8

Basic information

• Product Name: 2-(cyclopent-2-en-1-yl)propanoic acid
• CAS NO: 76337-97-8
• Molecular Formula: C₈H₁₂O₂
• Molecular Weight: 140.1797
• Mol File: 76337-97-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 251°C at 760 mmHg
• Flash Point: 148.3°C
• Density: 1.088g/cm³
• Vapor Pressure: 0.0066mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: 2-(cyclopent-2-en-1-yl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(cyclopent-2-en-1-yl)propanoic acid(76337-97-8)
• EPA Substance Registry System: 2-(cyclopent-2-en-1-yl)propanoic acid(76337-97-8)

Safety Data

• Hazardous Substances Data: 76337-97-8(Hazardous Substances Data)

Usage

General Description

2-(cyclopent-2-en-1-yl)propanoic acid, also known as 2-Cyclopentenylpropionic acid, is a carboxylic acid compound with the chemical formula C9H14O2. It is a colorless liquid with a slightly sweet odor and is commonly used in the pharmaceutical industry as a precursor for the synthesis of various drugs and bioactive molecules. 2-(cyclopent-2-en-1-yl)propanoic acid is also used in organic synthesis as a versatile building block for the preparation of various functionalized derivatives. Its structure consists of a cyclopentene ring attached to a propanoic acid group, making it a valuable reagent in the field of organic chemistry for the production of diverse chemical compounds.

Upstream product

• 35116-18-8 2-cyclopentenyl propanoate 
• 930-30-3 cyclopent-2-enone 
• 3212-60-0 cyclopent-2-enol 
• 134132-75-5 tert-Butyl-[(E)-1-(cyclopent-2-enyloxy)-propenyloxy]-dimethyl-silane 
• 53608-93-8 diethyl 2-(cyclopenten-1-yl)propane-1,3-dioate 
• 83974-29-2 cyclopent-2-enyl-methyl-malonic acid diethyl ester 

Downstream Products

• 76338-03-9 C₁₇H₂₄N₂O₃S 

Relevant articles and documents

Stereochemical Control in the Ester Enolate Claisen Rearrangement. 2. Chairlike vs Boatlike Transition-State Selection

The preference for chair-and boatlike transition-state geometries in the ester enolate Claisen rearrangement of straight chain, carbocyclic, and heterocyclic propanoates was investigated.A novel stereoelectronic effect in pyranoid and furanoid glycal systems leads to a significant relative stabilisation of the boatlike vs the chairlike TS(excit.).The preferred transition state in six- and five-membered carbocyclic systems is highly dependent on steric factors, as the energy difference between chair-and boatlike TS(excit.) tends to be small.With straight-chain substrates, a significant contribution of the boatlike TS(excit.) to the rearrangement product mixture is only expected in bis-donor substituted allylic esters.

TRICYCLO2,8>OCTANONES AS BUILDING BLOCKS IN NATURAL PRODUCTS SYNTHESIS (I). --THE SYNTHESIS OF CHRYSOMELIDIAL--

The stereocontrolled synthesis of chrysomelidial from 4-methyl-tricyclo2,8>octan-3-one is described.