76350-85-1 Usage
Uses
Used in Pharmaceutical Industry:
(2'-METHYLBIPHENYL-3-YL)-METHANOL is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with unique therapeutic properties. Its structural features allow for the creation of molecules with specific biological activities, making it a valuable component in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, (2'-METHYLBIPHENYL-3-YL)-METHANOL is utilized as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties enable the design of effective compounds targeting agricultural pests and weeds, thereby enhancing crop protection.
Used in Organic Chemistry as a Reagent:
(2'-METHYLBIPHENYL-3-YL)-METHANOL serves as a reagent in various organic chemistry reactions, facilitating the synthesis of complex organic molecules. Its functional groups, including the hydroxyl group, participate in a range of chemical transformations, making it a versatile component in organic synthesis.
Used in Organic Synthesis as a Building Block:
As a building block in organic synthesis, (2'-METHYLBIPHENYL-3-YL)-METHANOL is employed to construct more complex organic molecules. Its structural attributes allow for the formation of diverse molecular architectures, which can be further elaborated upon to achieve specific chemical and physical properties for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 76350-85-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,3,5 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 76350-85:
(7*7)+(6*6)+(5*3)+(4*5)+(3*0)+(2*8)+(1*5)=141
141 % 10 = 1
So 76350-85-1 is a valid CAS Registry Number.
76350-85-1Relevant academic research and scientific papers
Discovery of HWL-088: A highly potent FFA1/GPR40 agonist bearing a phenoxyacetic acid scaffold
Li, Zheng,Ren, Qiang,Wang, Xuekun,Zhou, Zongtao,Hu, Lijun,Deng, Liming,Guan, Li,Qiu, Qianqian
, (2019/09/06)
Based on a previously reported phenoxyacetic acid scaffold, compound 7 (HWL-088) has been identified as a superior free fatty acid receptor 1 (FFA1) agonist by comprehensive structure-activity relationship study. Our results indicated that the introduction of ortho-fluoro greatly increased the activity of phenoxyacetic acid series, and the unique structure-activity relationship in biphenyl moiety is different from previously reported FFA1 agonists. Moreover, the modeling study was also performed to better understand the binding mode of present series. Compound 7 significantly improved glucose tolerance both in normal and diabetic models, and even exerted greater potential on glucose control than that of TAK-875. These findings provided a novel candidate HWL-088, which is currently in preclinical study to evaluate its potential for the treatment of diabetes.
Pd-mediated C-C and C-S bond formation on solid support: A scope and limitations study
Wendeborn, Sebastian,Berteina, Sabine,Brill, Wolfgang K.-D.,De Mesmaeker, Alain
, p. 671 - 675 (2007/10/03)
The scope and limitations of Pd(0)-mediated coupling reactions between aromatic halides linked to a polystyrene resin and boronic acid derivatives (Suzuki coupling), aromatic and vinylic tin compounds (Stille coupling), as well as thiols are reported. For all reactions, conditions were optimized and evaluated with various reagents. In many cases, upon cleavage from the solid support, products were obtained in excellent yields. In most cases, the optimized reaction conditions are superior to those previously reported in the literature.
