76351-86-5 Usage
Properties
1. Complex chemical compound
2. Pyrimidinecarboxamide derivative
3. Contains amino and methoxy group
4. Contains nortropanyl group
5. Contains p-methylbenzyl moiety
6. Potential applications in pharmaceutical industry
7. May act as an inhibitor or modulator of biological processes
Specific content
1. Amino group
2. Methoxy group
3. Nortropanyl group
4. p-methylbenzyl moiety
5. Potential pharmaceutical applications
6. Mechanism of action not fully understood
7. Biological targets not fully identified
8. Further research needed to explore potential effects
Check Digit Verification of cas no
The CAS Registry Mumber 76351-86-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,3,5 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 76351-86:
(7*7)+(6*6)+(5*3)+(4*5)+(3*1)+(2*8)+(1*6)=145
145 % 10 = 5
So 76351-86-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H27N5O2/c1-13-3-5-14(6-4-13)12-26-16-7-8-17(26)10-15(9-16)24-19(27)18-11-23-21(22)25-20(18)28-2/h3-6,11,15-17H,7-10,12H2,1-2H3,(H,24,27)(H2,22,23,25)
76351-86-5Relevant academic research and scientific papers
Studies on the neuroleptic benzamides. III - Synthesis and antidopaminergic properties of new 3-nortropane derivatives
Dostert,Imbert,Langlois,et al.
, p. 105 - 110 (2007/10/02)
Various benzamides prepared from 4-alkoxy pyrimidine 5-carboxylic acids and 3-amino nortropane derivatives have been tested for their potential antipsychotic activity. Two compounds exhibited pharamacological activity equivalent to that of haloperidol but had lower toxicity and lower potency to induced catalepsy. Antidopaminergic activity is observed mainly in compounds in which the nortropane ring is substituted in the equatorial position, having a benzyl substituent on the basic nitrogen. The influence of electron attractor or donor substituents carried by the benzyl ring has been evaluated. Some aspects of structure-activity relationships are discussed.
