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1-(2-methoxyethyl)-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione, commonly known as compound 9e, is a highly potent hypoxia-selective cytotoxic agent. It is a compound with a unique chemical structure that includes a pyrimido[4,5-d][1,3]oxazin-2,4-dione scaffold, a phenyl ring, and a 2-methoxyethyl branch. 1-(2-methoxyethyl)-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione has been recognized for its significant potential in the treatment of cancer, particularly in targeting hypoxic tumor cells that are often resistant to standard chemotherapy treatments. Its effectiveness and low toxicity make it a promising candidate for drug development in cancer therapy.

76361-14-3

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76361-14-3 Usage

Uses

Used in Cancer Therapy:
1-(2-methoxyethyl)-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione is used as a hypoxia-selective cytotoxic agent for the treatment of cancer. It is particularly effective in targeting hypoxic tumor cells, which are known to be resistant to conventional chemotherapy treatments. 1-(2-methoxyethyl)-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione's high antitumor activity and low toxicity make it a valuable asset in the development of new cancer therapies.
Used in Drug Development:
1-(2-methoxyethyl)-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione is used as a potential candidate for drug development in the field of cancer therapy. Its unique chemical structure and high potency against hypoxic tumor cells offer a promising avenue for the creation of new, more effective cancer treatments. 1-(2-methoxyethyl)-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione's low toxicity further supports its potential for use in drug development, as it may lead to therapies with fewer side effects for patients.

Check Digit Verification of cas no

The CAS Registry Mumber 76361-14-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,3,6 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 76361-14:
(7*7)+(6*6)+(5*3)+(4*6)+(3*1)+(2*1)+(1*4)=133
133 % 10 = 3
So 76361-14-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H13N3O4/c1-21-8-7-18-13-11(14(19)22-15(18)20)9-16-12(17-13)10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3

76361-14-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-methoxyethyl)-7-phenylpyrimido[4,5-d][1,3]oxazine-2,4-dione

1.2 Other means of identification

Product number -
Other names 1-(2-methoxyethyl)-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:76361-14-3 SDS

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