76367-87-8 Usage
General Description
2-(5-methyl-4-oxohexyl)-1H-isoindole-1,3(2H)-dione, also known as SU4312, is a chemical compound with potential applications in the fields of medicinal chemistry and pharmacology. It belongs to the class of isoindolines and is commonly used as a research tool to study angiogenesis, the process of forming new blood vessels from pre-existing ones. 2-(5-methyl-4-oxohexyl)-1H-isoindole-1,3(2H)-dione has been found to exhibit inhibitory effects on various angiogenesis-related enzymes and has shown promise as a potential anti-cancer agent. Additionally, SU4312 has been studied for its potential neuroprotective effects and its ability to modulate neuroinflammation, making it a promising candidate for the development of new therapeutic agents for neurological disorders. Overall, 2-(5-methyl-4-oxohexyl)-1H-isoindole-1,3(2H)-dione is a versatile chemical with a wide range of potential applications in biomedical research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 76367-87-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,3,6 and 7 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 76367-87:
(7*7)+(6*6)+(5*3)+(4*6)+(3*7)+(2*8)+(1*7)=168
168 % 10 = 8
So 76367-87-8 is a valid CAS Registry Number.
76367-87-8Relevant articles and documents
Synthesis and Antimalarial Activity of 8--6-methoxy-4-methylquinolines
Yan, Shou-Jen,Chien, Ping-Lu,Cheng, C. C.
, p. 215 - 217 (1981)
Three analogues of the causal prophylactic antimalarial primaquine were prepared and their antimalarial activity was evaluated. 8--6-methoxy-4-methylquinoline (2a) demonstrated activity against Plasmodium berghei in mice at 20 mg/kg, with all animals cured at 320 mg/kg, and is without toxicity at 640 mg/kg.It also possessed outstanding causal prophylactic activity against Plasmodium cynomolgi in rhesus monkeys at very low dosages.
